CK-EXOGENE’S RESEARCH PAPERS

, a leader in the research and development of exosome-based therapies, plays a crucial role in Q Biomed’s technological advancements. Their cutting-edge research papers form the foundation of our innovative medical solutions, allowing us to integrate the latest scientific insights into our treatments. As a partner, CK-EXOGENE provides us with invaluable knowledge in exosome production, stem cell therapy, and regenerative medicine, making it possible for us to offer groundbreaking treatments for a wide range of conditions.

Here are some notable research papers from CK-EXOGENE that contribute to the development of Q Biomed’s medical technologies:

2020: "Apoptotic cell-derived exosomes: Messages from dying cells, Experimental & Molecular Medicine”

This paper explores the role of apoptotic cell-derived exosomes in cellular communication, which can be applied in targeted therapies for regenerative medicine and chronic disease treatments.

2021: "Possibility of exosome-based coronavirus vaccine (review), Molecular Medical Reports 25:26

This review investigates the potential of exosomes in vaccine development, contributing to the broader field of immune response therapies.

2022: "Transforming growth factor-B family and stem cell-derived exosome therapy in osteoarthritis (review), Int’l Journal of Molecular Medicine 49:62

This paper discusses how stem cell-derived exosomes can be used to treat osteoarthritis, a critical area of focus for Q Biomed’s Q JointRenew therapy.

2022: "Review of scar assessment scales, Medical Lasers: Engineering, Basic Research, and Clinical Application

This study looks into various methods for assessing scar formation and healing, which is relevant for Q ExoSkin Radiance, our aesthetic exosome solution.

2023: "Exosomal delivery of TRAIL and miR-335 for hepatocellular carcinoma treatment (review), Int’l Journal of Molecular Medicine 51:3”

Focusing on cancer therapy, this paper outlines how exosomes can be used to deliver therapeutic agents, highlighting the versatile applications of exosomes in various disease treatments.

2023: "Dermal fibroblast cell-derived exosomes for atopic dermatitis (in-vitro test), Wiley DOI:10.1111/srt.13382

The paper demonstrates how exosomes derived from dermal fibroblasts can be used to treat skin conditions like atopic dermatitis, reinforcing the scientific basis for Q ExoSkin Radiance

2023: "Role of Gasdermin E in the biogenesis of apoptotic cell-derived exosomes, The Journal of Immunology 2023, 210: 1-16”

This research investigates the role of Gasdermin E in the biogenesis of apoptotic cell-derived exosomes, offering deeper insights into the molecular mechanisms that support exosome-based therapies.

2023 “Cancer research from bench to bedside: A call for papers, The Lancet Oncology”

This call for papers further emphasizes the potential of exosome-based therapies in oncology, an area where CK-EXOGENE continues to make significant contributions.

CK-EXOGENE’S PATENT REGISTRATIONS

CK-EXOGENE holds numerous patents for the development of exosome-based technologies and production methods. These patents cover a wide range of innovations, from exosome production and applications to specific therapies targeting chronic diseases and cancers, which are integral to Q Biomed’s products, including the development and production of our MSC and exosome-based therapies.

List of Patents:

  • 2016 Korea 10-2316777 Exosome production control cells, composition containing the same, exosomes obtained therefrom and method for producing exosomes
  • 2020 PCT KR2020/008450 Method for producing exosomes derived from mesodermal stem cells and culture medium prepared thereform
  • 2020 Korea 10-2184428 Method for producing exosomes derived from mesodermal stem cells and culture medium prepared thereform
  • 2021 US 17/434, 117 Method for preparing mesenchymal stem cell-derived exosome and culture solution produced from the same
  • 2021 EU 20929677.1 Method for preparing mesenchymal stem cell-derived exosome and culture solution produced from the same
  • 2021 Korea 10-2316777 Exosome production control cells, composition containing the same, exosomes obtained therefrom and method for producing exosomes
  • 2021 Japan 2021-563388 Method for producing exosomes derived from mesodermal stem cells and culture medium prepared thereform
  • 2021 China 202080032199 Method for producing exosomes derived from mesodermal stem cells and culture medium prepared thereform
  • 2021 Korea 10-2021-0147279 Exosomes containing cartilage homeostasis factors and compositions containing the same for preventing or treating osteoarthristis
  • 2021 Korea 10-2021-0154283 Exosome-based antiviral vaccine and method for producing the same
  • 2021 Korea 10-2021-0191702 Exosome-based antiviral vaccine
  • 2021 Korea 10-2021-0191703 Exosome-based antiviral vaccine based on the exosomes platform
  • 2022 Korea 10-2022-0025206 Pharmaceutical composition for preventing or treating liver cancer containing exosomes
  • 2022 PCT KR2022/003331 Antiviral vaccine based on exosomes platform
  • 2022 Russia 202211154 Method for preparing mesenchymal stem cell-derived exosome and culture solution produced from the same
  • 2022 Brazil 11 2022 008056 5 Method for preparing mesenchymal stem cell-derived exosome and culture solution produced from the same
  • 2022 India 202217025138 Method for preparing mesenchymal stem cell-derived exosome and culture solution produced from the same
  • 2022 Korea 10-2427786 Method for preparing mesenchymal stem cell-derived exosome and culture solution produced from the same

2022 Thailand 2201007536 Method for preparing mesenchymal stem cell-derived exosome and culture solution produced from the same

CK-EXOGENE’S PATENT REGISTRATIONS

CK-EXOGENE’s intellectual property is pivotal in shaping the future of exosome-based treatments, and their continued innovations are a major factor in the ongoing success of Q Biomed’s medical technologies.

Ongoing Developments

CK-EXOGENE is also at the forefront of developing exosome-based vaccines for shingles, flu, and AIDS, with promising progress in these areas. These ongoing developments further highlight the expanding potential of exosome therapies and their broad applications in both therapeutic and preventive medicine.

Through our partnership with CK-EXOGENE, Q Biomed is committed to bringing the most advanced, scientifically validated treatments to our patients, paving the way for better health outcomes in a wide range of medical conditions.